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The major metabolite of carisoprodol, meprobamate, is an approved anxiolytic. Retrospective, where can I order soma cheapest Irvine post-marketing studies do not show a where can I order soma cheapest Irvine consistent association between maternal consumption of meprobamate and an increased risk of birth defects in particular. Animal studies have where can I order soma cheapest Irvine not adequately evaluated the teratogenic effects where can I order soma cheapest Irvine of carisoprodol. There was no increased incidence of congenital malformations noted in reproductive studies in rats, rabbits and mice treated with meprobamate. Retrospective, post-marketing studies of meprobamate during human pregnancy are equivocal for demonstrating an increased risk of birth defects following exposure during the first quarter. Among the studies that have shown an increased risk of malformations incompatible types. In animal studies, carisoprodol reduced fetal weights, weight gain after birth, and postnatal survival at maternal doses equivalent to 1 to 1.5 times the human dose (based on a comparison of body surface). Rats exposed to meprobamate in utero showed behavioral alterations that persist into adulthood. For children exposed in utero to meprobamate, a study found no negative effect on mental or motor development or IQ scores. SOMA should be where can I order soma cheapest Irvine used during pregnancy only if the where can I order soma cheapest Irvine potential benefit justifies the risk to the fetus.

No information on the effects of SOMA on the mother and fetus during labor.

Very limited data in humans show that SOMA is present in breast milk and may reach concentrations two to four times the levels of maternal plasma. In one reported case, a breastfed baby where can I order soma cheapest Irvine receives about 4-6% of the maternal daily dose through breast milk and experienced no adverse effects. However, milk production was inadequate and that the baby was supplemented with formula. In studies of lactation in mice, the survival of women and newborn weightsmall at weaning was reduced.

These data suggest that maternal use of SOMA can lead to the reduction of infant feeding or less effective (due to sedation) and / or decreased milk production. Caution where can I order soma cheapest Irvine should be exercised when SOMA is where can I order soma cheapest Irvine administered OF a nursing woman.

The efficacy, safety and pharmacokinetics of SOMA where can I order soma cheapest Irvine in pediatric patients under 16 years have not been established. The efficacy, safety and pharmacokinetics of SOMA in patients over 65 have not been established. The safety and pharmacokinetics of SOMA in patients with renal impairment have not been evaluated. Since SOMA is excreted by the kidneys, caution should be exercised if SOMA is administered to patients with renal failure. Carisoprodol is where can I order soma cheapest Irvine dialyzable by hemodialysis and peritoneal dialysis. The safety and pharmacokinetics of SOMA in patients with hepatic impairment have not been evaluated.

Since SOMA is metabolized in the liver, caution should be where can I order soma cheapest Irvine exercised when administered to patients with liver failure of Somas. Patients with reduced activity CYP2C19 have higher exposure where can I order soma cheapest Irvine to carisoprodol. Therefore, caution should be exercised in the administration of SOMA to where can I order soma cheapest Irvine these patients. The basic measures of life support should be instituted as dictated by the clinical presentation of the SOMA overdose. Induced nausea and where can I order soma cheapest Irvine vomiting is not recommended due to risk of CNS and respiratory depression, which can increase the risk of aspiration pneumonia.

Gastric lavage should be considered soon after ingestion (within an hour).

Circulatory support should be administered by infusion volume and vasopressors, if necessary. Convulsions where can I order soma cheapest Irvine should be treated with intravenous benzodiazepines and recurrence of seizures can be treated with phenobarbital. In case of severe depression of the central nervous system, reflexes, respiratory protection may be compromised where can I order soma cheapest Irvine and tracheal intubation should be considered for airway protection and respiratory support. The following types of treatment have been used successfully by an overdose of meprobamate, a metabolite of SOMA: where can I order soma cheapest Irvine activated charcoal (oral or nasogastric tube), forced where can I order soma cheapest Irvine diuresis, peritoneal dialysis and hemodialysis (carisoprodol is dialyzable). Careful monitoring of urine output is necessary and overhydration should be avoided.

Observed relapse due to the absorption of delayed gastric emptying incomplete.